Linking at the US National Library of Medicine     

Kent A. Smith  Ed Sequeira 《Learned Publishing》2001,14(1):23-28

The development of services provided by the National Library of Medicine (NLM), which dates back to 1836, is described. MEDLINE, a database of 10-plus million references and abstracts to the world's biomedical literature, was put on the World Wide Web for free searching in 1997 as a system called PubMed, whose use has grown to over 250 million searches per year. PubMed features a variety of links between MEDLINE references and related information – full-text journal articles, DNA sequence data, medical knowledge bases, etc. – at websites within and outside NLM. PubMed is a major component of a larger NLM system, Entrez, which integrates access to a number of genome-related databases with linking features similar to those of PubMed. The newest linked service, which became a reality in February 2000, is PubMed Central, the National Institutes of Health's free repository for primary research reports in all the life sciences.  相似文献   

The influence of crank rate on peak oxygen consumption during arm crank ergometry   总被引：1，自引：0，他引：1  

Smith PM  Price MJ  Doherty M 《Journal of sports sciences》2001,19(12):955-960

The aim of this study was to assess the influence of three imposed crank rates on the attainment of peak oxygen consumption (VO2peak) and other physiological responses during incremental arm crank ergometry. Twenty physically active, although non-specifically trained, males volunteered for the study. They completed an exercise protocol using an electrically braked arm ergometer (Lode Angio, Groningen, Netherlands) at crank rates of 60, 70 and 80 rev x min(-1). The order of tests was randomized and they were separated by at least 2 days. Peak VO2 was significantly higher (P < 0.05) at 70 and 80 rev x min(-1) than at 60 rev x min(-1). Peak ventilation volume increased as a function of crank rate and was higher (P < 0.05) at 80 than at 60 rev x min(-1). Peak heart rate was higher (P < 0.05) at 70 and 80 rev x min(-1) than at 60 rev x min(-1). Furthermore, 70 and 80 rev x min(-1) resulted in an extended test time compared with 60 rev x min(-1). The greater physiological responses observed during the tests at the two faster crank rates might have been the result of a postponement of acute localized neuromuscular fatigue, allowing for more work to be completed. We recommend, therefore, that an imposed crank rate between 70 and 80 rev x min(-1) should be used to elicit VO2peak and other physiological responses in arm crank ergometry.  相似文献   

Response of males and females to high-force eccentric exercise     

Rinard J  Clarkson PM  Smith LL  Grossman M 《Journal of sports sciences》2000,18(4):229-236

It has previously been shown that females incur less muscle damage than males after strenuous exercise, but limited data are available for humans. To determine possible differences between the sexes in humans, the response to high-force eccentric exercise was examined in a large sample of women (n = 83) and men (n = 82). The participants performed a bout of eccentric exercise of the elbow flexors consisting of 70 maximal repetitions. Isometric strength, resting elbow angle and muscle soreness were measured before, immediately after (except soreness) and then daily for 7 days after exercise. There was a significant loss in strength among both groups (69% for women and 63% for men) (P < 0.01) immediately after exercise; at 168 h post-exercise, women still had a 27% strength loss and men had a 24% strength loss. No significant difference in strength loss or recovery rate was found between men and women. Soreness reached peak values 32-48 h post-exercise (P < 0.01), with no significant difference between men and women. Range of motion decreased significantly until 3 days after exercise (14.6 degrees or 0.255 rad loss for women; 12.2 degrees or 0.213 rad loss for men) (P < 0.01); at 168 h post-exercise, the women and men still showed a loss of 4.8 degrees (0.084 rad) and 4.0 degrees (0.07 rad), respectively. There was a significant interaction of sex x time (P < 0.01); a post-hoc test indicated that the women experienced a greater loss in range of motion at 72 h than men and this difference was maintained to 168 h post-exercise (P < 0.01). Thus, our results do not support the contention that women have a lower response to eccentric exercise than men.  相似文献   

Faith,Class and Politics: The Role of the Churches in Teacher Training, 1914–1945, by Mark Lofthouse     

John Smith 《History of education》2013,42(1):123-125

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A Curriculum Laboratory     

Leslie A. Smith 《课程研究杂志》2013,45(2):109-114

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2000 Elections     

Jeffrey Smith 《Educational Measurement》1999,18(3):4-4

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Does Chewing Coca Leaves Influence Physiology at High Altitude?     

Casikar V  Mujica E  Mongelli M  Aliaga J  Lopez N  Smith C  Bartholomew F 《Indian journal of clinical biochemistry : IJCB》2010,25(3):311-314

Andean Indians have used coca leaves (Erythroxylon coca and related species) for centuries to enhance physical performance. The benefits and disadvantages of using coca leaf have been a subject of many political debates. The aim of this study was to investigate the effects of chewing coca leaves on biochemical and physiological parameters. Cutaneous microdialysis catheters were used to estimate systemic biochemical changes. We subjected 10 healthy adult males (local residents) in Cajamarca (Peru, altitude 2700 m) to a standardised exercise routine on a stationary cycle ergometer. The blood pressure, oxygen saturation (digital), pulse, VO2 max and ECG (Holter monitor) were recorded before the exercise. Cutaneous microdialysis catheters were introduced in the forearm. The subjects were given to chew 8 g of coca leaves with a small amount of lime. They were then placed on the cycle ergometer for 20 min. Blood pressure, oxygen saturation, pulse, ECG and VO2 max were recorded. Pyruvate, glucose, lactate, glycerol and glutamate levels were estimated. Oxygen saturation, blood pressure, and pulse rate did not show any significant changes between the two groups. Glucose levels showed hyperglycaemic response. Glycerol, Lactate and Pyruvate increased. Glutamate remained unchanged. Similar changes were not seen in the controls. These results suggest that coca leaves have blocked the glycolytic pathway of glucose oxidation resulting in accumulation of glucose and pyruvate. The energy requirement for exercise is being met with beta-oxidation of fatty acids. The glycerol released was also getting accumulated since its pathway for oxidation was blocked. These experimental findings suggest that chewing coca leaves is beneficial during exercise and that the effects are felt over a prolonged period of sustained physical activity.  相似文献   

Building Future Directions for Teacher Learning in Science Education     

Kathy Smith  Simon Lindsay 《Research in Science Education》2016,46(2):243-261

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Describing the plastic deformation of aluminium softball bats   总被引：1，自引：1，他引：0  

Eric Biesen  Lloyd Smith 《Sports Engineering》2007,10(4):185-193

Hollow aluminium bats were introduced over 30 years ago to provide improved durability over wooden bats. Since their introduction, however, interest in hollow bats has focused almost exclusively around their hitting performance. The aim of this study was to take advantage of the progress that has been made in predicting bat performance using finite elements and apply it to describe bat durability. Accordingly, the plastic deformation from a ball impact of a single-wall aluminum bat was numerically modelled. The bat deformation from the finite-element analysis was then compared with experiment using a high-speed bat test machine. The ball was modelled as an isotropic, homogeneous, viscoelastic sphere. The viscoelastic parameters of the ball model were found from instrumented, high-speed, rigid-wall ball impacts. The rigid-wall ball impacts were modelled numerically and showed good agreement with the experimentally obtained response. The strain response of the combined bat-ball model was verified with a strain-gauged bat at intermediate ball impact speeds in the elastic range. The strain response of the bat-ball model exhibited positive correlation with the experimental measurements. High-speed bat-ball impacts were performed experimentally and simulated numerically at increasing impact speeds which induced correspondingly increased dent sizes in the bat. The plastic deformation from the numerical model found good agreement with experiment provided the aluminium work hardening and strain rate effects were appropriately described. The inclusion of strain rate effects was shown to have a significant effect on the bat deformations produced in the finite-element simulations. They also helped explain the existence of high bat stresses found in many performance models.  相似文献   

The influence of photographic developers containing hydrazine upon the characteristic curves of photographic materials. I     

R. Eliot Stauffer  W.F. Smith  A.P.H. Trivelli 《Journal of The Franklin Institute》1944,238(4):291-298

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